HealthConnexion is located at #11-08


Gynecological Cancers



In Singapore, gynecological cancers are among the top 10 cancers affecting women, with uterine, ovarian, and cervical cancers being especially prominent. Uterine cancer is the 4th most common, ovarian cancer the 5th, and cervical cancer ranks 10th among female cancers locally. Despite our advanced healthcare system, screening rates for cervical cancer have declined in recent years, contributing to ongoing challenges in early diagnosis and mortality reduction. 

Early detection is a critical factor in improving outcomes, as symptoms are often non-specific and may not appear until the later stages of the disease.


Common Gynecological Cancers in Singapore

Latest data show the most common gynecological cancers among Singaporean women from 2017 to 2021 were:

  • Uterine Cancer
    The most prevalent gynecological cancer in Singapore, ranking as the 4th most common cancer for women overall.

     
  • Ovarian Cancer
    This ranks as the 5th most common cancer among women in Singapore. 
    It is also the deadliest gynecological cancer due to late-stage detection; up to 80% are diagnosed after the disease has spread.

     
  • Cervical Cancer
    Ranking as the 10th most common cancer for women in Singapore, its incidence has been declining over the years due to screening programs and the HPV vaccine.


Symptoms of Gynecological Cancers

While symptoms can vary by type, early detection can be challenging as they are often non-specific and may be mistaken for other conditions. Common symptoms include:

  • Uterine Cancer
    Usually presents with abnormal uterine bleeding, especially after menopause.

     
  • Ovarian Cancer 
    Symptoms typically appear late and include pelvic pain, bloating, difficulty eating, and urinary symptoms.

     
  • Cervical Cancer
    May show irregular bleeding (after sex, between periods, post-menopause), foul-smelling discharge, or pelvic pain in advanced stages. Often asymptomatic early on, making screening essential.

     


Treatment Approaches of Gynecological Cancers

Treatment for gynecological cancers is often a multidisciplinary effort involving gynecological oncologists, radiation oncologists, and medical oncologists. Treatment plans are highly individualized and depend on the type of cancer, its stage, and the patient's overall health. The main treatment modalities include:

  • Uterine Cancer
    Surgical options include hysterectomy, with radiation and hormone therapy for some cases.

     
  • Ovarian Cancer
    Treated with surgery (removal of ovaries, uterus, lymph nodes) and chemotherapy, especially in advanced stages. Early detection dramatically improves survival rates.

     
  • Cervical Cancer
    Early stages treated with surgery; advanced stages may require radiotherapy and chemotherapy. Preventive measures include Pap smear and HPV testing. HPV vaccination is widely available and encouraged in Singapore


Treatment Modalities for Gynecological Cancers

Specific treatment plans will depend on several factors, including the type of cancer, its stage, and overall health. A multidisciplinary team, often led by a gynecologic oncologist, will work with patients to determine the best course of action, which may involve surgery, chemotherapy, radiation therapy, or a combination of these approaches. Ongoing research is also leading to new therapies, such as immunotherapy and targeted therapies, which are providing more personalized and effective treatments.

  • Surgery
    This is often the primary treatment for most gynecological cancers. Procedures can range from removing just the cancerous tissue to a more extensive hysterectomy (removal of the uterus), salpingo-oophorectomy (removal of the ovaries and fallopian tubes), and lymph node removal.

     
  • Radiotherapy
    This uses high-energy rays to kill cancer cells. It can be used after surgery to destroy any remaining cancer cells or as a primary treatment for locally advanced cancers. Brachytherapy is an essential part of curative treatment for many cases of cervical cancer, with High-Dose-Rate (HDR) and Low-Dose-Rate (LDR) options.

     
  • Chemotherapy
    This involves using powerful drugs to kill cancer cells throughout the body. It can be administered intravenously or orally and is often used in combination with surgery or radiotherapy.

     
  • Targeted Therapy and Immunotherapy
    These are newer treatment options that specifically target cancer cells or help the body's immune system to fight the cancer. They are used for specific types and stages of gynecological cancers.
     




Novel Antibody-Based Approaches for Cancer Therapy

New therapies use the body's natural immune system components and modify them into highly targeted and powerful weapons against cancer. Antibodies locate and bind to cancer cells, acting like a "smart bomb" to deliver the toxic drug directly to the tumor, minimizing damage to healthy tissues. Medical oncologist Dr. Hsieh Wen-Son shares more.

Read the story
 



Understanding Cancer: Your Guide to Diagnosis, Treatment, and Support

Advancements in medical technology today offer hope despite the rising incidence of cancer worldwide. With a comprehensive approach to cancer care, including support from experienced clinical oncologists, specialists, and healthcare professionals, many cancers may be effectively treated or managed.


Empowering Yourself with Knowledge

This resource provides information about cancer, including:

  • Types of Cancer: Learn about different forms of cancer and their specific characteristics.
  • Early Detection: Understand the importance of cancer screening for early diagnosis and better treatment outcomes.
  • Treatment Options: Explore various cancer treatments, including surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy.
  • Financial Assistance: Discover available financial aid options to help manage the cost of cancer care.
  • Reducing Your Risk: Learn about lifestyle factors and preventive measures to minimize your cancer risk.


What is Cancer?

Cancer is a group of diseases characterized by the uncontrolled growth of abnormal cells in the body. Normally, the body replaces old or damaged cells with new ones. However, genetic mutations or other factors can disrupt this process, leading to the formation of abnormal cells that multiply uncontrollably and form tumors.

Types of Tumors:

  • Benign Tumors: Non-cancerous tumors that do not spread to other parts of the body.
  • Malignant Tumors: Cancerous tumors that can spread to other parts of the body, also known as metastasis.


What Causes Cancer?

Cancer is caused by a complex interplay of factors, including:

  • Non-Modifiable Factors: Age, family history, and inherited genetic mutations.
  • Modifiable Factors:
    • Lifestyle: Diet, smoking, and alcohol consumption.
    • Environmental Exposures: Radiation, ultraviolet rays, pollutants, and certain viruses and bacteria.


Symptoms of Cancer

Cancer symptoms vary depending on the type and location. However, some general signs and symptoms include:

  • Fatigue
  • Unexplained weight loss
  • Swelling or lumps
  • Skin changes
  • Persistent cough or headaches
  • Unusual bleeding or bruising


Important Note: These symptoms may also be indicative of other health conditions. Speak to our Specialists today for a proper evaluation and diagnosis.


Common Cancers in Singapore

  • Men
    Colorectal cancer
    is also known as bowel cancer and rectal cancer, and is a disease in which the cells in the colon and rectum mutate and change.

    Prostate cancer occurs specifically in the prostate, located below the bladder and in front of the rectum, where cells mutate to form tumors that may be localized or spread to nearby tissues.

    Lung cancer is a disease in which cells in the lungs mutate to form tumors that interfere with the lung's primary function of taking in oxygen and releasing carbon dioxide.

  • Women
    Breast cancer
    develops in breast tissue where tumors form, and most breast cancers begin in the ducts and glands of breasts.

    Colorectal cancer is also known as bowel cancer and rectal cancer and is a disease in which the cells in the colon and rectum mutate and change.

    Lung cancer is a disease in which cells in the lungs mutate to form tumors that interfere with the lung's primary function of taking in oxygen and releasing carbon dioxide,


Cancer Treatment Goals

  • Complete tumor removal.
  • Prevention of cancer recurrence or spread.
  • Symptom management and palliative care.


Cancer Prevention

While there's no guaranteed way to prevent cancer, you may reduce your risk by:

  • Avoiding smoking and excessive alcohol consumption.
  • Maintaining a healthy weight and balanced diet.
  • Getting regular exercise.
  • Undergoing recommended cancer screenings.
  • Getting vaccinated against certain cancer-causing viruses (e.g., HPV).


Farrer Park Cancer Care is supported by a panel of multi-disciplinary oncology experts to guide patients and their caregivers on their cancer journey; using innovative approaches to cancer treatments with new technologies, personalized care plans and therapies.

From understanding a cancer diagnosis to deciding on a treatment plan, we are here to meet the spectrum of needs required by our patients, providing them with clinical care and working together to make informed decisions as we navigate with them through the disease into remission.