Please be informed HealthConnexion has moved to #11-08

Common Cancers in Singapore: A Deep Dive into Prostate Cancer

  • 24 Feb 2025
  • 5 mins

Cancer is characterized as the uncontrolled proliferation of cells that result in the growth of tumors; over time, the cancer cells may spread to other parts of the body. Cancer can start anywhere in the human body.

In a normal human body, human cells will grow and multiply to form new cells when the body needs them. As the cell becomes old or damaged, they will die, and new cells will be created to take its place. However, sometimes this process malfunctions, resulting in the growth or multiplication of cells when there shouldn’t be any. These cells may eventually form a lump of tissue known as a tumor, which can be either cancerous or non-cancerous.

According to the Singapore Cancer Society prostate cancer is the most common cancer among Singaporean man. 6,912 cases have been diagnosed between 2017 to 2021, accounting for 16.8% of all male cancers in Singapore. 

We sit down with Urologist Dr. Lee Fang Jann to look at the signs and symptoms of prostate cancer, what screenings are available to help detect the cancer early, what you could possibly do to lower your risk of developing this cancer, and more.


Prostate Cancer Prostate is the most common cancer among Singaporean men, accounting for 18% of all cancers diagnosed in men. It happens when cancer cells form in the prostate, a walnut-sized gland located between the penis and bladder. Prostate cancer may be difficult to detect in its early stages, as it does not present any symptoms. It also shares similar symptoms with benign prostate hyperplasia, a non-cancerous enlargement of the prostate.

Signs and symptoms

  • Difficulty urinating
  • Weak or interrupted flow of urine
  • Frequent urination, particularly at night
  • Urinary retention (trouble emptying the bladder)
  • Blood in the urine or semen
  • Pain or burning during urination
  • Pain in the back, hip, or pelvis that does not go away
  • Painful ejaculation

Risk Factors

Non-Modifiable Risk Factors Modifiable Risk Factors
  • Male gender
  • Age
  • Family history
  • Inherited gene mutations
  • Alcohol consumption
  • Low physical activity
  • Being overweight or obese
  • Diet rich in dairy product and meat
  • Smoking
  • Consumption of processed food
  • Exposure to certain chemicals
  • Poor sleep quality

Prostate cancer incidences strongly increase with age, particularly among older men between the ages of 70–74. In addition, while high dietary intake of dairy products and meat has been linked to an increased risk of prostate cancer, it has been noted that frequent consumption of tomatoes, cruciferous vegetables, and soy foods may provide protection against prostate cancer.

Screening

Although there is currently no standard or routine screening tests, there are tests that can be performed to screen for the possibility of prostate cancer.

Digital Rectal Exam: It involves your doctor or nurse feeling your prostate through the lower part of your rectum to see if you might have a prostate problem or prostate cancer.

Prostate-Specific Antigen Test: A Prostate-Specific Antigen (PSA) test measures the level of PSA in your blood. PSA is a substance produced by the prostate that may be found in elevated levels in men with prostate cancer. However, a high level of PSA may also be a sign of benign prostate hyperplasia or an infection or inflammation of the prostate.

According to Dr. Lee Fang Jann, screening for prostate cancer is recommended in men aged 50 and above.

“However, for those at higher risk, screening may start as early as age 40 or 45,” he adds. “It’s important to have a conversation with your doctor to weigh the benefits and risks of screening, as overdiagnosis and overtreatment can be concerns.”

There are often no noticeable signs of early-stage prostate cancer hence, as Dr. Lee explains, why screening is so important. “In some cases, men may experience urinary symptoms such as difficulty urinating, weak urine flow, or frequent urination, but these are more commonly caused by non-cancerous conditions like BPH,” Dr. Lee explains.

If any abnormalities are found during the screening, further diagnostic tests such as a prostate biopsy or advanced imaging may be performed to confirm the diagnosis.

Treatment

Treatment for your prostate cancer will depend on several factors, such as how fast it is growing and whether it has spread to other parts of your body.

For men low-risk prostate cancer, you may not need to be treated right away. Instead, your doctor may recommend active surveillance to monitor the prostate cancer and treat it only if there are signs of it progressing. This is due to the fact that low-risk prostate cancer often grows very slowly or doesn't grow at all, so treatment often isn’t needed.

Other treatment options include surgery to remove the prostate gland, sometimes through minimally invasive methods such as the Robotic-assisted laparoscopic prostatectomy, which according to Dr. Lee, “offers greater precision and faster recovery times.”

Prevention

  • Improve your diet: A higher dairy intake has been associated with an increased risk of developing prostate cancer. It was observed that low fat milk intake was associated with greater risk of non-aggressive form of the disease and whole milk was associated with greater risk of fatal prostate cancer. Instead, you can focus on incorporating more fruits and leafy greens into your diet, as well as green tea and soy.
  • Maintain a healthy weight: Studies show that obesity is a significant risk factor for prostate cancer. Maintaining a healthy weight as you age also helps you lower your risk of prostate cancer as well as other health problems.
  • Exercise regularly: Regular exercise helps you achieve a healthy weight, as well as improve immune function and fights off the negative effects of a sedentary lifestyle.
  • Stop smoking: Although the link between smoking and prostate cancer is still uncertain and being studied, current experiments that had been taken to study their relationships have observed an association between smoking and prostate cancer, with smokers having a 24% higher risk of death from prostate cancer than non-smokers.
  • Limit or stay away from alcohol: High alcohol intake, especially binge drinking, has been associated with an increased risk of Prostate Cancer. It may accelerate the growth of prostate tumors and significantly shorten the time for the progression of metastatic prostate cancer.
  • Increase your Vitamin D: Although traditionally involved with bone health, vitamin D is becoming increasingly recognized for its broader impact on immune health and cancer prevention. Studies have noted a link between vitamin D deficiency and elevated prostate cancer risk.